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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0860L | Mefloquine | Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998 | Others |
Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l... | |||
T77552 | SLU-PP-1072 | Apoptosis , Estrogen/progestogen Receptor | |
SLU-PP-1072 is an ERRα and ERRγ inverse dual agonist that disrupts PCa cell metabolism and induces apoptosis through cell cycle dysregulation.SLU-PP-1072 is used to study prostate cancer (PCa). | |||
TN1805 | Isosilybin B | Apoptosis , Androgen Receptor | |
Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes to G1-phase blockade and apoptosis.Isosilybin B induces degr... | |||
TN1804 | Isosilybin A | Apoptosis , Tyrosinase , PPAR , ABC | |
Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio... | |||
T41175 | OB 24 hydrochloride | ||
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in adv... |